Un estudio investiga la suplementación en la enfermedad renal crónica

Autor : Strive Health

Según un estudio de 2017 publicado en American Family Physician1, entre el 40% y el 60% de los adultos estadounidenses con una enfermedad crónica utilizan suplementos dietéticos. Aunque estos productos no se consideran medicamentos y pueden comprarse en una variedad de negocios en línea y al por menor, pueden causar daño al paciente por sí mismos o interactuar con los medicamentos prescritos a los pacientes causando una interacción de medicamentos.

La interacción puede deberse a la forma en que el cuerpo absorbe, distribuye, metaboliza o excreta el suplemento (farmacocinética) o al efecto directo que el suplemento tiene en el cuerpo (farmacodinámica).

Los efectos de una interacción farmacocinética pueden mitigarse ajustando la dosis del suplemento o del medicamento, pero sólo si se conoce el mecanismo de interacción, lo que no es habitual.

Una interacción farmacodinámica es mucho menos probable. En general, hacer que el paciente deje de tomar el suplemento es la mejor opción para prevenir la interacción.

De los 15 suplementos dietéticos a base de hierbas mencionados en el estudio del American Family Physician de 2017, el cohosh negro, el arándano, el ginkgo, el ginseng americano, el cardo mariano, la palma enana americana y la valeriana mostraron indicios de un riesgo potencial bajo de interacciones farmacológicas. Mientras que los experimentos con el sello de oro y la hierba de San Juan indicaron un alto riesgo potencial de interacciones farmacológicas.

Hay que señalar que este estudio sólo muestra indicios de posibles interacciones y no ha sido corroborado ni establecido como hecho. Antes de tomar cualquier decisión sobre la suplementación, consulte con su nefrólogo o médico.

En la atención centrada en el paciente, es importante mantener las líneas de comunicación abiertas para que los pacientes compartan su uso de suplementos con el proveedor. Igualmente importante es que el proveedor tenga recursos a los que acudir para poder realizar la investigación necesaria para determinar si los suplementos podrían ser más perjudiciales que beneficiosos.

1: https://pubmed.ncbi.nlm.nih.gov/28762712/

 


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